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| First Name: | Akihiko | | Last Name: | Nunomura | | Title: | Associate Professor | | Advanced Degrees: | MD, PhD | | Affiliation: | Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi | | Department: | Department of Neuropsychiatry | | Street Address 1: | 1110 Shimokato | | City: | Chuo | | State/Province: | Yamanashi | | Zip/Postal Code: | 409-3898 | Country/Territory: | Japan | | Phone: | +81-55-273-9847 | | Fax: | +81-55-273-6765 | | Email Address: |  |
Disclosure:
(view policy)
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Member reports no financial or other potential conflicts of interest. [Last Modified: 15 May 2012]
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View all comments by Akihiko Nunomura
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Aging Process, Alzheimer Disease
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Molecular and Cell biology, Oxidative Stress, Apoptosis/Cell cycle, Neuropathology
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[Academic Degrees]
1986: M.D. Asahikawa Medical College, Asahikawa, Japan
1991: Ph.D. Asahikawa Medical College, Asahikawa, Japan
[Professional Experience]
1991-1992: Resident, Department of Psychiatry and Neurology, Asahikawa Medical College, Asahikawa, Japan
1992-1997: Instructor, Department of Psychiatry and Neurology, Asahikawa Medical College, Asahikawa, Japan
1997-1999: Research Fellow, Institute of Pathology, Case Western Reserve University, Cleveland, Ohio, USA
1999-2000: Instructor, Department of Psychiatry and Neurology, Asahikawa Medical College, Asahikawa, Japan
2000-2004: Assistant Professor, Department of Psychiatry and Neurology, Asahikawa Medical College, Asahikawa, Japan
2004-2008: Associate Professor, Department of Psychiatry and Neurology, Asahikawa Medical College, Asahikawa, Japan
2008-: Associate Professor, Department of Neuropsychiatry, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Chuo, Yamanashi, Japan
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1) Nunomura A, et al. The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons. J Neuropathol Exp Neurol 71:233-41, 2012 [PMID: 22318126]
2) Nunomura A, et al. Intraneuronal amyloid β accumulation and oxidative damage to nucleic acids in Alzheimer disease. Neurobiol Dis 37: 731-7, 2010 [PMID: 20034567]
3) Nunomura A, et al. RNA oxidation in Alzheimer disease and related neurodegenerative disorders. Acta Neuropathol 118:151-66, 2009 [PMID: 19271225]
4) Nunomura A, et al. Involvement of oxidative stress in Alzheimer disease. J Neuropathol Exp Neurol 65:631-41, 2006 [PMID: 16825950]
5) Nunomura A, et al. Neuronal RNA oxidation is a prominent feature of familial Alzheimer’s disease. Neurobiol Dis 17:108-13, 2004 [PMID: 15350971]
6) Nunomura A, et al. Oxidative damage is the earliest event in Alzheimer disease. J Neuropathol Exp Neurol 60:759-67, 2001 [PMID: 11487050]
7) Nunomura A, et al. Neuronal oxidative stress precedes amyloid-β deposition in Down syndrome. J Neuropathol Exp Neurol 59:1011-7, 2000 [PMID: 11089579]
8) Perry G, et al. Amyloid β junkies. Lancet 355:757, 2000 [PMID: 10703837]
9) Nunomura A, et al. RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer’s disease. J Neurosci 19:1959-64, 1999 [PMID: 10066249]
10) Perry G, et al. A suicide note from Alzheimer disease neurons? Nat Med 4:897-8, 1998 [PMID: 9701239]
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